Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy
Tel: +39 0571 568 147 e 0571 568 135
vb@vincibiochem.it
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Chimerigen
Immune Regulation Proteins -
The Experts for High Quality Fusion Proteins
Chimerigen produce una varietà di
citochine chimeriche
, non litiche, basate su Ig, con una lunga emivita di circolazione per facilitarne lo studio degli effetti
In Vivo
. Una sequenza di citochina è geneticamente fusa alla regione cerniera
di una immunoglobulina,
insieme ai domini CH2 e CH3. Queste proteine di fusione non litiche possiedono sia le funzioni biologiche della frazione di citochina sia una prolungata emivita di circolazione, determinata dal dominio Fc. Le mutazioni nei siti di legame del complemento (C1q) e FcgR I del frammento Fc delle IgG rendono le proteine di fusione incapaci di citotossicità diretta dagli anticorpi (ADCC) e di citotossicità diretta dal complemento (CDC). Queste molecole di fusione promettono anche di essere minimamente o trascurabilmente immunogeniche poiché sono interamente composte da elementi derivati dalla specie da trattare. Distributore esclusivo in Italia Vinci-Biochem Srl.
Vedi anche
.
Immune Regulation Proteins - Chimerigen
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Focus: Immune Checkpoint Proteins, Interleukins & Cytokines
Technical Note: Non-lytic Ig-based Chimeric Fusion Cytokines with Long Circulating Half-life
Mouse Immune Checkpoint & Interleukin Proteins for In Vivo Studies
Human Cytokines
B7-CD28 Superfamily
Other Immune Checkpoint Proteins
TIM Family
Butyrophilin-like 2
Costimulation & Immune Regulation Factors
Interleukins & Cytokines
Specific IL-15Ra Antagonist
Immunomodulating Cytokines & Growth Factors
Inflammatory Chemokines
Stem Cell Factor [SCF]
Control Fusion Proteins
Product
Code
Size
Price €
Preventivo / Ordina
ACE2 (HUMAN) (REC.) (HIS)
Purity:
>90% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-B232008-C100
100 µg
inquire
ACE2 (HUMAN):FC (HUMAN) (REC.)
Purity:
>90% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-B232006-C100
100 µg
inquire
B7-H3(4IG) [B7-H3B] (HUMAN) (REC.) (HIS)
Purity:
>95% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-201B7H3B-C050
50 µg
inquire
B7-H3(4IG) [B7-H3B] (HUMAN):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-211B7H3B-C100
100 µg
inquire
B7-H4 (HUMAN) (REC.)
Purity:
>95% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-200B7H4-C050
50 µg
inquire
B7-H4 (HUMAN) (REC.) (HIS)
Purity:
>95% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-201B7H4-C050
50 µg
inquire
B7-H4 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210B7H4-C100
100 µg
inquire
B7-H4 (HUMAN):FC (MOUSE) (REC.)
Purity:
>95% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-211B7H4-C100
100 µg
inquire
B7-H4 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-110B7H4-C100
100 µg
inquire
B7-H5 [VISTA] (HUMAN) (REC.) (HIS)
Purity:
>95% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-201B7H5-C050
50 µg
inquire
B7-H6 (HUMAN):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-211B7H6-C100
100 µg
inquire
BMP-2 (HUMAN) (REC.) (HIS)
Purity:
>95% (SDS-PAGE)
Source / Host:
E. coli
CHI-HR-200BMP2-C010
10 µg
inquire
BMP-2 (HUMAN) (REC.) (HIS)
Purity:
>95% (SDS-PAGE)
Source / Host:
E. coli
CHI-HR-200BMP2-C050
50 µg
inquire
BMP-2 (HUMAN):FC (HUMAN) (REC.) (NON-LYTIC)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-220BMP2-C050
50 µg
inquire
BTNL2 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-110BTNL2-C100
100 µg
inquire
CCL20 (HUMAN):FC (HUMAN) (REC.)
Purity:
>95% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-210CCL20-C050
50 µg
inquire
CCL20 (MOUSE):FC (MOUSE) (REC.)
Purity:
>95% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-MF-110CCL20-C050
50 µg
inquire
CCL22 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CCL22-C050
50 µg
inquire
CCL22 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-110CCL22-C050
50 µg
inquire
CCL24 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CCL24-C050
50 µg
inquire
CCL4 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CCL4-C050
50 µg
inquire
CCL5 (HUMAN) (REC.) (HIS)
Purity:
>98% (SDS-PAGE)
Source / Host:
E. coli
CHI-HR-200CCL5-C050
50 µg
inquire
CD27 (HUMAN) (REC.) (HIS)
Purity:
>97% (SDS-PAGE)
Source / Host:
E. coli
CHI-HR-200CD27-C050
50 µg
inquire
CD27 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD27-C100
100 µg
inquire
CD28 (HUMAN) (REC.) (HIS)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-201CD28-C100
100 µg
inquire
CD28 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD28-C200
200 µg
inquire
CD28 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-110CD28-C200
200 µg
inquire
CD38 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-210CD38-C100
100 µg
inquire
CD38 (HUMAN):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-211CD38-C100
100 µg
inquire
CD40 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD40-C100
100 µg
inquire
CD40L [CD154] (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD40L-C050
50 µg
inquire
CD45 (HUMAN):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-211CD45-C050
50 µg
inquire
CD54 [ICAM-1] (HUMAN):FC (HUMAN) (REC.) (NON-LYTIC)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-220ICAM1-C100
100 µg
inquire
CD54 [ICAM-1] (MOUSE):FC (MOUSE) (REC.) (NON-LYTIC)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-120ICAM1-C050
50 µg
inquire
CD56 (HUMAN):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-211CD56-C050
50 µg
inquire
CD68 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD68-C100
100 µg
inquire
CD74 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-MF-110CD74-C100
100 µg
inquire
CD80 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD80-C100
100 µg
inquire
CD80 (HUMAN):FC (MOUSE) (REC.)
Purity:
>95% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-211CD80-C100
100 µg
inquire
CD80 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-110CD80-C100
100 µg
inquire
CD83 (HUMAN):FC (HUMAN) (REC.) (NON-LYTIC)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-220CD83-C100
100 µg
inquire
CD83 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-110CD83-C050
50 µg
inquire
CD86 (HUMAN):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-211CD86-C100
100 µg
inquire
CD86 (MOUSE):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-MF-110CD86-C100
100 µg
inquire
CD134 [OX40] (HUMAN) (REC.) (HIS)
Purity:
>97% (SDS-PAGE)
Source / Host:
E. coli
CHI-HR-200CD134-C025
25 µg
inquire
CD134 [OX40] (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD134-C050
50 µg
inquire
CD134 [OX40] (HUMAN):FC (MOUSE) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-HF-211CD134-C100
100 µg
inquire
CD134 [OX40] (MOUSE):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
HEK 293 cells
CHI-MF-111CD134-C100
100 µg
inquire
CD137 (HUMAN) (REC.) (HIS)
Purity:
>95% (SDS-PAGE)
Source / Host:
E. coli
CHI-HR-200CD137-C025
25 µg
inquire
CD137 (HUMAN):FC (HUMAN) (REC.)
Purity:
>98% (SDS-PAGE)
Source / Host:
CHO cells
CHI-HF-210CD137-C100
100 µg
inquire
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