Mps1-IN-3
CAY-41029-50 50 mg
Synonyms: Monopolar Spindle 1 Inhibitor 3|Monopolar Spindle1-IN-3|Mps1 Inhibitor 3
Data Sheet: 
SDS:
SDS:
CAS
1609584-72-6
Formulation
A solid
Purity
≥98%
MW
537,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An Mps1 inhibitor (IC50 = 50 nM); inhibits the proliferation of U251 glioblastoma cells (IC50 = ~5 µM); prevents nocodazole-induced checkpoint-mediated mitotic arrestin U2OS osteosarcoma cells at 2 µM; induces nuclear aberrancies and chromosome missegregation defects in U251-FM-H2B-GFP cells at 5 µM in combination with vincristine or paclitaxel; sensitizes U251-FM cells to vincristine and increases survival in an orthotopic mouse model of glioblastoma at 2 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
