Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

Mps1-IN-3

  CAY-41029-25 25 mg

 
Synonyms: Monopolar Spindle 1 Inhibitor 3|Monopolar Spindle1-IN-3|Mps1 Inhibitor 3
 
Cayman
Mps1-IN-3

Data Sheet:     SDS:    

CAS
1609584-72-6  

Formulation
A solid  

Purity
≥98%  

MW
537,6  

Shipment
-20  

Long Term Storage
-20  

Shelf Life
1460  


Description
 
An Mps1 inhibitor (IC50 = 50 nM); inhibits the proliferation of U251 glioblastoma cells (IC50 = ~5 µM); prevents nocodazole-induced checkpoint-mediated mitotic arrestin U2OS osteosarcoma cells at 2 µM; induces nuclear aberrancies and chromosome missegregation defects in U251-FM-H2B-GFP cells at 5 µM in combination with vincristine or paclitaxel; sensitizes U251-FM cells to vincristine and increases survival in an orthotopic mouse model of glioblastoma at 2 mg/kg
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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