
CAS
1379545-95-5
Formulation
A solid
Purity
≥98%
MW
449,9
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dual inhibitor of p70S6K and Akt1 (IC50s = 1.1 and 4 nM, respectively); selective for p70S6K and Akt1 over Aurora B kinase (IC50 = 170 nM), as well as a panel of 265 kinases at 1 µM; inhibits PKA, MSK1, MSK2, PKG1α, PKG1β, and PRKX; reduces tumor volume in A549 and MiaPaCa-2 mouse xenograft models at doses of 20 or 30 mg/kg, respectively
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).