Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

K03861

  CAY-19921-50 50 mg


Data Sheet:     SDS:    

CAS
853299-07-7  

Formulation
A solid  

Purity
≥98%  

MW
501,5  

Shipment
-20  

Long Term Storage
-20  

Shelf Life
1460  


Description
 
A Cdk2 inhibitor; binds to wild-type Cdk2, Cdk2C118L, Cdk2A144C, and Cdk2C118L/A144C (Kds = 50, 18.6, 15.4, and 9.7 nM, respectively); selectively inhibits proliferation of IL-3-stimulated Ba/F3 cells expressing FLT3-ITD over wild-type Ba/F3 cells (IC50s = ~0.001 and > 0.1 µM, respectively); inhibits human cytomegalovirus replication in primary human monocyte-derived macrophages (IC50 = 1.028 µM); inhibits spindle organization and chromosome alignment in meiosis I and prevents egg activation in isolated mouse oocytes at 10 µM
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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