
CAS
853299-07-7
Formulation
A solid
Purity
≥98%
MW
501,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A Cdk2 inhibitor; binds to wild-type Cdk2, Cdk2C118L, Cdk2A144C, and Cdk2C118L/A144C (Kds = 50, 18.6, 15.4, and 9.7 nM, respectively); selectively inhibits proliferation of IL-3-stimulated Ba/F3 cells expressing FLT3-ITD over wild-type Ba/F3 cells (IC50s = ~0.001 and > 0.1 µM, respectively); inhibits human cytomegalovirus replication in primary human monocyte-derived macrophages (IC50 = 1.028 µM); inhibits spindle organization and chromosome alignment in meiosis I and prevents egg activation in isolated mouse oocytes at 10 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).