Alloisolithocholic Acid
CAY-29542-5 5 mg
Synonyms: AILCA|AlloisoLCA|IsoalloLCA|Isoallolithocholic Acid|NSC 18169|β-hydroxy-5-Cholenoic Acid
CAS
2276-93-9
Formulation
A solid
Purity
≥95%
MW
376,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A metabolite of dehydrolithocholic acid; increases the association of Nr4a1 to the Foxp3 gene locus in isolated mouse CD4+ T cells at 20 µM; induces differentiation of isolated mouse T cells into Tregs and the production of mitochondrial ROS in isolated mouse CD4+ T cells at 20 µM; reduces hepatic bile flow and bile salt, cholesterol, and phospholipid secretion, as well as induces loss of microvilli and dilation of canaliculi in hepatocytes in rats at 6 mg/kg; fecal levels are reduced in patients with Crohn's disease or ulcerative colitis
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
