trans-Indole-3-acrylic acid
AG-CR1-3677-M250 250 mg
Synonyms: IAcrA; trans-3-Indoleacrylic acid; trans-beta-Indoleacrylic acid; (E)-3-(1H-Indol-3-yl)acrylic acid; NSC29428; NSC137806; BRN0006317
Data Sheet: 
SDS:
SDS:
CAS
29953-71-7
Purity
>98%
MW
187.2
Shipment
Ambient
Short Term Storage
+4°C
Long Term Storage
+4°C
Shelf Life
Stable for at least 2 years after receipt when stored at +4°C.
Description
Chemical. CAS: 29953-71-7. Formula: C11H9NO2. MW: 187.2. Synthetic. Inflammation suppressor. Tryptophan metabolite produced by human microbiota (intestinal commensale Peptostreptococcus sp). Involved in keeping the intestinal barrier intact and works as anti-inflammatory molecule. Patients with Inflammatory bowel Disease (IBD) have an altered microbiota, with less Peptostreptococcus sp., and therefore reduced production of trans-indole-3-acrylic acid. Chromophoric L-Trp analog used to probe the allosteric properties of the internal aldimine of tryptophan synthas. Also shown to be a moderate inhibitor of tryptophan synthase, trypothan-2,3-dioxygenase, indoleamine-2,3-dioxygenase, L-dopachrome isomerase and xanthine oxidase. Reagent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize and analyze polyphenols and synthetic polymers. Used as heterocyclic building block or intermediate for the synthesis of indolyl acrylamide-derived inhibitors, pharmaceuticals or agrochemicals.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
