diABZI STING Agonist-1
CAY-42079-5 5 mg
Synonyms: diABZI Stimulator of Interferon Genes Agonist 1|Diamidobenzimidazole Stimulator of Interferon Genes Agonist 1|Diamidobenzimidazole STING Agonist 1|Stimulator of Interferon Genes Agonist (Compound 3)|STING Agonist (Compound 3)
Data Sheet: 
SDS:
SDS:
CAS
2138498-18-5
Formulation
A solid
Purity
≥98%
MW
849,9
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An activator of the STING pathway; induces secretion of IFN-β in human PBMCs (EC50 = 130 nM); increases serum levels of Ifn-β, Il-6, Tnf, and Cxcl1 in wild-type, but not Sting-/-, mice at 2.5 mg/kg; inhibits the cytopathic effect of HCoV-229E in infected MRC-5 cells (EC50 = 3 nM); decreases the level of SARS-CoV-2 RNA in primary human bronchial airway epithelial cells in an air-liquid interface assay; decreases tumor volume and increases survival in a CT26 murine colorectal cancer model at 3 mg/kg; this compound is expected to exist in one or both tautomeric forms
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
