XST-14
CAY-43722-25 25 mg
Data Sheet: 
CAS
2607143-50-8
Formulation
A solid
Purity
≥98%
MW
291,347
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A ULK1 inhibitor (IC50 = 13.6 nM); selective for ULK1 over ALK2, p38α MAPK, TGFBR2, and MEK1 (IC50s = 183.8, 283.9, 809.3, and 721.8 nM, respectively) but does inhibit CaMKII and ULK2 (IC50s = 66.3 and 70.9 nM, respectively); induces apoptosis and autophagy and decreases invasion in HepG2 cells at 5 µM; decreases tumor volume alone and in combination with sorafenib in a HepG2 mouse xenograft model
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
