WNK463
CAY-37673-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
2012607-27-9
Formulation
A solid
Purity
≥95%
MW
463,456449
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A WNK1-4 inhibitor (IC50s = 5, 1, 6, and 9 nM, respectively); selective for WNK1-4 over a panel of 442 kinases at 10 µM; decreases blood pressure, as well as increases urine output and urinary sodium and potassium excretion rates in SHRs at 1, 3, and 10 mg/kg; decreases tumor growth, induces intratumoral apoptosis, and increases intratumoral levels of CD4+ and CD8+ T cells in an MC-38 mouse syngeneic colon cancer model at 5 and 10 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
