CAS
890764-36-0
Formulation
A solid
Purity
≥98%
MW
384,395
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A positive allosteric modulator of mGluR5 (Ki = 250 nM); potentiates glutamate-induced calcium flux in HEK293 cells expressing rat mGluR5 (EC50 = 10.7 nM); prevents ethanol-induced memory impairments in the novel object recognition test in rats at 30 mg/kg; reverses ethanol-induced conditioned place preference in rats at 10 mg/kg for ten days, an effect that can be reversed by MTEP or MK-801
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).