Synonyms: Vacuolar Protein Sorting 34 Inhibitor 1|VPS34 Inhibitor 1


CAS
1383716-33-3
Formulation
A crystalline solid
Purity
≥98%
MW
425,9
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A potent and selective inhibitor of VPS34 (IC50 = 25 nM in vitro); dose-dependently inhibits generation of PtdIns-(3)-p, which is essential to the formation and trafficking of endsomes and autophagosomes, without affecting the ability of class I PI3K to regulate Akt; induces a rapid and pronounced loss of phosphorylation on serum- and glucocorticoid-regulated kinase 3
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).