Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (untagged)
SBB-CE0011-C050 50 µg
Synonyms: Ubiquitin E1 Enzyme; Ubiquitin-like Modifier-activating Enzyme 1; A1S9T; AMCX1; GXP1; POC20; SMAX2
![Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (untagged)](/images/loghi/NoImage-logoVB.png "Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (untagged)")
Data Sheet: 
Reactivity
Human
Source / Host
Sf21 cells
Purity
>95% (SDS-PAGE)
MW
~118kDa
Shipment
DRY ICE
Short Term Storage
-80°C
Long Term Storage
-80°C
Shelf Life
Stable for at least 1 year after receipt when stored at -80°C.
Description
Protein. Human UBA1 (aa1-2-1058)is untagged. Source: Sf21 cells. Formulation: Liquid. In 50mM HEPES pH 7.5, 150mM sodium chloride, 10% glycerol, 2mM TCEP. Purity: >95% (SDS-PAGE). UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate intermediate is formed, then transferred to the E1’s active site cysteine through a thioester bond. This thioester is then transferable to an E2 conjugating enzyme’s active site cysteine.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
