CAS
1118460-77-7
Formulation
A solid
Purity
≥98% (mixture of isomers)
MW
422,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A noncompetitive inhibitor of EAAT1; selective for EAAT1 over EAAT2 and EAAT3 (IC50s = 0.66, >300, and >300 µM, respectively); selective for human EAAT1 (Kd = 0.34 µM) over rat EAAT4 and mouse EAAT5 at concentrations up to 10 µM in an electrophysiology study; orally bioavailable in rats at a dose of 10 mg/kg but does not cross the blood-brain barrier
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).