Tropisetron (hydrochloride)
CAY-21240-1 1 g
Synonyms: ICS 205-930|SDZ-ICS 930
Data Sheet: 
SDS:
SDS:
CAS
105826-92-4
Formulation
A crystalline solid
Purity
≥98%
MW
320,8
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A 5-HT3 receptor antagonist (Ki = 0.8 nM for the mouse receptor); selective for 5-HT3 over 5-HT4 (Ki = 156 nM for the porcine receptor); an antagonist of the α9 nAChR (IC50 = 166 nM for the rat receptor); a partial agonist of α7 nAChR (Ki = 6.9 nM for the rat receptor); enhances glycine-induced potentiation of homomeric α1 but not homomeric α2 glycine receptors at 10 µM; blocks 5-HT-induced depolarizations in isolated rabbit nodose ganglia at 0.1 nM; exhibits anti-emetic effects in a ferret model of cisplatin-induced emesis at 1 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
