Treprostinil (diethanolamine salt)
CAY-11927-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
830354-48-8
Formulation
A crystalline solid
Purity
≥98%
MW
495,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An agonist of IP2, DP2, and EP2 receptors; binds selectively to IP2, DP2, and EP2 over EP1, EP3, and EP4 receptors (Kis = 32, 4.4, 3.6, 212, 2,505, and 826 nM, respectively, in radioligand binding assays); inhibits LPS-induced production of TNF-α, IL-1β, IL-6, and GM-CSF in in isolated human alveolar macrophages at 200 ng/ml; relaxes isolated small pulmonary arteries and veins precontracted with U-46619; reduces right ventricular systolic pressure compared to hypoxic and sham control animals in a mouse model of chronic hypoxic pulmonary hypertension
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
