Thiomyristoyl
CAY-19398-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1429749-41-6
Formulation
A crystalline solid
Purity
≥98%
MW
581,9
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A potent and selective SIRT2 inhibitor (IC50s = 0.028, 98, >200, and >200 μM for SIRT2, SIRT1, SIRT3, and SIRT5-7, respectively); inhibits acetyl-H3K9 peptide and NAD binding to SIRT2 and promotes c-Myc degradation in a dose-dependent manner; exhibits selective cytotoxicity (IC50s = 8.4-36.8 and >50 μM for cancerous and non-cancerous cell lines, respectively); decreases tumor volume and increases areas of necrosis in an MDA-MB-231 mouse breast cancer xenograft model; increases tumor-free survival time in a MMTV-PyMT mouse mammary tumor model
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
