
CAS
1234365-97-9
Formulation
A crystalline solid
Purity
≥98%
MW
1217,97104
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An orally bioavailable NHE-3 inhibitor (IC50 = 10 nM for the recombinant rat protein); inhibits intestinal fluid absorption in mouse jejunum, but not distal colon, in a closed intestine loop assay at 10 µM; lowers both the sodium and phosphate urinary-to-dietary ratio in a dose-dependent manner in rats; reverses loperamide-induced decreases in stool pellet numbers and water content and prevents loperamide-induced constipation in mice at 5 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).