
CAS
332012-40-5
Formulation
A crystalline solid
Purity
≥98%
MW
409,82564
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A multi-kinase inhibitor; inhibits VEGFR2, VEGFR3, PDGFRα, and c-Kit (IC50s = 6, 4, 15, and 1 nM, respectively); binds to the transmembrane region of the ABCG2 efflux transporter and enhances intracellular accumulation of [3H]-mitoxantrone in ABCG2-overexpressing cells; decreases tumor growth rate and size in an H460/MX20 mouse xenograft model at 15 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).