Talabostat (mesylate)
CAY-29007-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
150080-09-4
Formulation
A solid
Purity
≥95%
MW
310,1765
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A non-selective inhibitor of DPPs (IC50s = >4, 310, 4, 11, 560, and 390 nM for DPP-4, DPP-7, DPP-8, DPP-9, FAP, and PREP, respectively); inhibits proliferation of superantigen-stimulated human PBMCs (IC50 = ~10 nM); increases expression of a variety of cytokines and chemokines in tumors and tumor-draining lymph nodes in a WEHI-164 fibrosarcoma mouse model at 5 μg twice per day; reduces tumor growth in a variety of syngeneic mouse models; increases the efficacy of the antitumor antibodies rituximab and trastuzumab in Namalwa B cell lymphoma and LS180 colon carcinoma mouse xenograft models, respectively
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
