CAS
865609-72-9
Formulation
A solid
Purity
≥98%
MW
463,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A GRK2 inhibitor; selectively inhibits phosphorylation of bovine rod outer segments by GRK2 (IC50 = 54 nM) over phosphorylation by GRK1 and GRK5 at concentrations up to 125 µM; inhibits phosphorylation of bovine rod outer segments by GRK2 containing various mutations, including GRK2L271M, GRK2Y206S, GRK2I197L, and GRK2L235G (IC50s = 24, 55, 106, and 180 nM, respectively)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).