TP-0472993
CAY-39757-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
2126874-77-7
Formulation
A solid
Purity
≥98%
MW
300,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A CYP4A11 and CYP4F2 inhibitor (IC50s = 140 and 40 nM, respectively); selective for CYP4A11 and CYP4F2 over a panel of eight additional CYPs at 10 µM; inhibits 20-HETE production in rat renal microsomes (IC50 = 347 nM); inhibits 20-HETE production in rats from 0.03-1 mg/kg; reduces renal fibrosis and IL-1β and TNF-α levels in a mouse model of folic acid-induced nephropathy and a mouse model of unilateral ureteral obstruction-induced neuropathy at 3 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
