TM-N1324
CAY-37208-10 10 mg
Data Sheet: 
CAS
1144477-35-9
Formulation
A solid
Purity
≥98%
MW
397,793503
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A GPR39 agonist; selective for GPR39 over a panel of 165 GPCRs, including GHS-R and the motilin receptor, at 1 µM; induces inositol phosphate accumulation in HEK293 cells expressing human GPR39 (EC50s = 2 and 201 nM in the presence and absence of zinc, respectively) and cAMP accumulation in COS-7 cells expressing human GPR39 (EC50 = 17 nM in the presence of zinc); decreases ghrelin secretion and increases somatostatin secretion in isolated mouse gastric mucosa cells at 1 µM; decreases food intake during the dark period and body weight in a mouse model of high-fat diet-induced obesity
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
