CAS
927878-49-7
Formulation
A crystalline solid
Purity
≥98%
MW
487,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An H-PGDS inhibitor (IC50 = 0.083 µM); selective for H-PGDS over L-PGDS and mPGES at 100 µM; selective for H-PGDS over COX-1, COX-2, 5-LO, LTC4 synthase, and TX synthase, as well as the histamine H1 and CysLT1 receptors, at 10 µM; inhibits antigen-induced increases in the production of PGD2 in nasal cavity lavage fluid and reduces nasal blockage in a guinea pig model of allergic rhinitis at 30 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).