CAS
948841-07-4
Formulation
A crystalline solid
Purity
≥98%
MW
336,2
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A potent and selective MAO-B inhibitor (Kis = 110 and 1,450 nM for MAO-B and MAO-A, respectively); interacts with the catalytic site of human MAO-B in a reversible and competitive manner (activity increases from 37% to 97% following inhibitor washout, indicating TB5 binding is reversible); demonstrates permeability in a PAMPA blood-brain barrier model; has minimal cytotoxicity (>84% cell viability) in HepG2 cells at a concentrations up to 25 μM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).