TAS 0728
CAY-33528-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
2088323-16-2
Formulation
A crystalline solid
Purity
≥98%
MW
504,5844
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A covalent HER2 inhibitor (IC50 = 36 nM); selective for HER2 over panels of 386 and 374 additional kinases, as well as a panel of 68 non-kinase enzymes, at 1 µM; inhibits HER2 autophosphorylation in HER2-overexpressing SK-BR-3 cells; inhibits the growth of six HER2-amplified cancer cell lines (GI50s = 1.6-31 nM); reduces tumor volume in NCI N87 and BT474 mouse xenograft models
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
