CAS
1223001-53-3
Formulation
A solid
Purity
≥98%
MW
293,295203
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of STK16 (IC50 = 295 nM); selective for STK16 over mTOR, PI3Kδ, and PI3Kγ (IC50s = 5,560, 856, and 867 nM, respectively, in an enzyme assay) and over 440 additional kinases in a KinomeScan profiling assay; decreases the growth of MCF-7 cells (GI50 = ~10 µM); potentiates the antiproliferative effects of colchicine, paclitaxel, doxorubicin, and cisplatin in MCF-7 cells at 2.5-5 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).