SR 1001
CAY-10922-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1335106-03-0
Formulation
A crystalline solid
Purity
≥98%
MW
477,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs at 5 μM; 25 mg/kg twice/day delays onset and severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
