SRT 2104
CAY-28380-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1093403-33-8
Formulation
A crystalline solid
Purity
≥98%
MW
516,64
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A SIRT1 activator; increases renal SIRT1 activity and protein levels and decreases acetylation of p53 in a mouse model of STZ-induced diabetes, as well as in non-diabetic control animals, at 100 mg/kg in the diet; decreases renal levels of iNOS, ROS, and MDA, as well as the fibrotic markers TGF-β1 and CTGF and the inflammatory markers PAI-1 and VCAM-1, in STZ-induced diabetic mice; increases lifespan, improves motor function in the balance beam test, and reduces atrophy of the neocortex in the N171-82Q mouse model of Huntington’s disease at 0.5% in the diet
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
