Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

SRS11-92

  CAY-25689-10 10 mg


Data Sheet:     SDS:    

CAS
1467047-25-1  

Formulation
A crystalline solid  

Purity
≥98%  

MW
352,5  

Shipment
-20  

Long Term Storage
-20  

Shelf Life
1460  


Description
 
A ferroptosis inhibitor and a derivative of ferrostatin-1; inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells (EC50 = 6 nM); inhibits iron-induced cell death in isolated mouse kidney proximal tubules at 2 µM; protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia at 100 nM; increases survival of medium spiny neurons in rat corticostriatal brain slices in an in vitro model of Huntington’s disease; increases production of ROS in L. major promastigotes at 3 µM; is toxic to L. major promastigotes (LD50 = 3.34 µM)
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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