CAS
1629138-41-5
Formulation
A crystalline solid
Purity
≥98%
MW
329,47976
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An activator of TGF-β signaling; reduces increases in Aβ42-induced cell death and the number of dystrophic neurites in primary mouse embryonic forebrain neurons at 3 µM; increases phagocytosis of Aβ42 by > 20% in J774A.1 and THP-1 macrophages; increases contextual fear conditioning freezing time and spontaneous alternations in the Y-maze, indicating prevention of memory deficits, in the APP751Lon,Swe transgenic mouse model of Alzheimer’s disease at 10 mg/kg for 10 weeks
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).