CAS
1357349-91-7
Formulation
A solid
Purity
≥98%
MW
277,324
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A RET inhibitor (IC50 = 0.008 µM); selective for RET over a panel of 44 serine/threonine/tyrosine kinases at 10 µM but does inhibit nine by >75%; selective for RET over a panel of 63 receptor and non-receptor tyrosine kinases 0.4 µM but does inhibit six, including RET, by >75%; reduces the proliferation of HCT116 and TPC-1 cells (EC50s = 2.4 and 3.3 µM, respectively); inhibits viral replication in FMDV-infected BHK-21 cells at 5 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).