SB-505124
CAY-11793-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
694433-59-5
Formulation
A crystalline solid
Purity
≥98%
MW
335,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An ALK5 and ALK4 inhibitor (IC50s = 47 and 129 nM, respectively); selective for ALK5 and ALK4 over a panel of 27 kinases at 10 µM; inhibits ALK7-induced increases in phosphorylated SMAD2 levels in COS-1 cells overexpressing ALK7 at 5 µM; inhibits TGF-ß-induced but not TNF-a-induced apoptosis in Fao cells at 1 µM; decreases IOP and subconjunctival immune cell infiltration in a rabbit model of trabeculectomy at 5 mg/eye
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
