CAS
143797-62-0
Formulation
A solid
Purity
≥98%
MW
302,75866
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dual antagonist of 5-HT2C (Ki = 125 nM in isolated rat cortex) and 5-HT2B receptors (pA2 = 7.5 in rat stomach fundus preparations); selective for 5-HT2C and 5-HT2B over 5-HT1A, 5-HT2A, 5-HT1D, 5-HT3, benzodiazepine, GABAA, α1-, α2A-, α2B-, β1-, and β2-adrenergic, dopamine D1 and D2, and histamine H1 receptors (Kis = >10 µM for all); reverses mCPP-induced hypophagia and decreases in social interaction time in rats at 20 and 40 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).