CAS
1062243-51-9
Formulation
A crystalline solid
Purity
≥98%
MW
543,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A selective Plk1 inhibitor (IC50s = 3 and 6 nM in an enzymatic assay and H82 lung cancer cells, respectively); over 500-fold selective over a panel of 318 kinases; inhibits tumor growth in a mouse xenograft model; increases autophagy and mTOR phosphorylation in NB4 cells; induces apoptosis in cancer cell lines
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).