Rheb Inhibitor NR1
CAY-43360-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
2216763-38-9
Formulation
A solid
Purity
≥98%
MW
578,302
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A Rheb inhibitor; inhibits Rheb-dependent mTORC1 activity (IC50 = 2.1 µM); selectively inhibits Rheb-depedent mTORC1 activity over Rheb-independent mTORC1 activity, mTORC2, Ras, and Rap1 at 30 µM; decreases the size of Jurkat T cells and inhibits protein synthesis in MCF-7 breast cancer cells at 10 µM; inhibits the phosphorylation of the mTORC1 substrates S6 and 4E-BP1 in mouse skeletal muscle and kidneys at 30 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
