Recombinant SMMHC Antibody / Smooth Muscle Myosin Heavy Chain
NSJ-V9683-100UG 100 ug
Data Sheet: 
Reactivity
Human
Applications
IHC-P
Source / Host
Rabbit
Immunogen
A portion of amino acids 1-100 of Myosin protein was used as the immunogen for the recombinant SMMHC antibody.
Clone
MYH11/7087R
Purity
Protein A/G affinity
Long Term Storage
Aliquot the recombinant SMMHC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Description
Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early and is specific for smooth muscle development. SM-MHC stains the intact myoepithelial cell (MEC) layers present in benign and in situ malignant breast and bronchioloalveolar lesions and is therefore very helpful in distinguishing between benign and malignant tumors. The antibody reacts with smooth muscle cells and myoepithelial cells, but not with myofibroblasts. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
