
CAS
1446790-62-0
Formulation
A solid
Purity
≥90%
MW
355,43768
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A Syk inhibitor (IC50 = 5.6 nM); selective for Syk over a panel of 392 other kinases at 1 µM; inhibits M. tuberculosis PknG (IC50 = 4.4 µM); inhibits the proliferation of, and induces apoptosis in, primary AML cells at 5 µM; prevents RANKL- and M-CSF-induced osteoclastogenesis in isolated mouse BMDMs (IC50 = 145 nM); reduces disease severity in a mouse model of collagen-induced arthritis at 5 or 45 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).