RG-7112
CAY-25673-5 5 mg
SDS: 
CAS
939981-39-2
Formulation
A crystalline solid
Purity
≥98%
MW
727,78368
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of the MDM2-p53 interaction (IC50 = 0.018 µM); inhibits proliferation in cancer cell lines expressing wild-type p53 (IC50s = 0.18-2.2 µM) and cell lines expressing mutant p53 (IC50s = 5.7-20.3 µM); prevents and reduces tumor growth in an SJSA-1 mouse xenograft model at 50 and 100 mg/kg per day, respectively; decreases platelet counts in rats at 50 and 100 mg/kg and in cynomolgus monkeys at 10 and 20 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
