Q-VD-OPh
AG-CP3-0006-M005 5 mg
Synonyms: Q-Val-Asp-OPh; pan-Caspase Inhibitor; N-(2-Quinolyl)-L-valyl-L-aspartyl-(2,6-difluorophenoxy) methylketone
Data Sheet: 
SDS:
SDS:
Source / Host
Synthetic.
CAS
1135695-98-5 (anhydrous)
Purity
>95% (TLC)
MW
513.5
Shipment
BI
Short Term Storage
+4°C
Long Term Storage
-20°C
Shelf Life
Stable for at least 3 years after receipt when stored at -20°C.
Description
Chemical. CAS: 1135695-98-5 (anhydrous). Formula: C26H25F2N3O6. MW: 513.5. Synthetic. Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
