Pyrvinium (pamoate)
CAY-31546-500 500 mg
Data Sheet: 
SDS:
SDS:
CAS
3546-41-6
Formulation
A solid
Purity
≥95%
MW
575,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An anthelmintic and anticancer agent; dietary administration reduces worm burden in mouse models of N. dubius, S. obvelata, or A. tetraptera infection (EC50s = 292, 4, and 17 ppm, respectively); lethal to mice at higher concentrations (LC50 = 600 ppm in the diet); induces cytotoxicity in PANC-1 cells cultured in glucose-deficient medium, but not serum- or amino acid-deficient medium or complete medium, at 1 μg/ml; reduces tumor growth in a PANC-1 mouse xenograft model at 100 μg/mouse per day; binds to and activates CK1α at 10 nM; inhibits Wnt signaling (EC50 = ~10 nM in a reporter assay) in a CK1α-dependent manner
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
