PF-3084014
CAY-27061-5 5 mg
Data Sheet: 
CAS
1290543-63-3
Formulation
A solid
Purity
≥98%
MW
489,644346
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of γ-secretase (IC50s = 6.2 and 1.2 nM, respectively, in an enzyme assay and in whole cells); does not induce Notch-related toxicity (EC50s = 1,300-3,000 nM for B cells in fetal thymic organ cultures); reduces the level of Aβ40 fragments in mouse brain three hours following 1 to 18 mg/kg doses and the level of Aβ42 fragments levels at 9 or 18 mg/kg; reduces Aβ fragments when at 0.3-3 mg/kg per day for five days
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
