PDGFR TKI III
CAY-14925-10 10 mg
Synonyms: PDGFR Tyrosine Kinase Inhibitor III|Platelet-derived Growth Factor Receptor TKI III|Platelet-derived Growth Factor Receptor Tyrosine Kinase Inhibitor III
Data Sheet: 
SDS:
SDS:
CAS
205254-94-0
Formulation
A solid
Purity
≥98%
MW
485,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A PDGFRα and PDGFRβ inhibitor (IC50s = 0.05 and 0.13 µM, respectively); selective for PDGFRα and PDGFRβ over FGFR, EGFR, PKA, and PKC (IC50s = 29.7, >30, >30, and >30 µM, respectively) but does inhibit c-Kit and FLT3 (IC50s = 0.05 and 0.23 µM, respectively); inhibits PDGF homodimer-induced proliferation of pig aorta smooth muscle cells (IC50 = 0.25 µM); inhibits the migration of primary mouse DA-MSCs induced by embryonic mouse blood at 2 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
