Synonyms: 8-Oxoberberine|Berlambine|JKL 1073A|NSC 93138


CAS
549-21-3
Formulation
A solid
Purity
≥98%
MW
351,35272
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An alkaloid and metabolite of berberine with diverse biological activities; reduces viability of SW480 cells at 1-200 µg/ml; increases the ratio of phosphorylated to unphosphorylated PI3K, Akt, and GSK-3β in isolated rat pancreatic tissue at 50 and 100 mg/kg; reduces rat blood glucose levels in an oral glucose tolerance test in a model of STZ-induced diabetes at 50 and 100 mg/kg; reduces inflammation and hepatosteatosis in a rat model of high-fat diet-induced NAFLD
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).