OTX008
CAY-23130-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
286936-40-1
Formulation
A crystalline solid
Purity
≥98%
MW
937,2
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of Gal-1; decreases lactose binding to Gal-1 (Kds = 290 and 100 μM in the presence and absence of compound, respectively); cytotoxic against a cancer cell panel with IC50 values that directly correlate to Gal-1 mRNA expression; inhibits proliferation of HUVECs (IC50 = 2 μM) and reduces HUVEC migration in a wound healing assay; reduces tumor growth in the MA148 ovarian mouse xenograft model and the B16 murine melanoma syngeneic model via decreases in tumor microvessel density and induction of apoptosis (2.4 and 10 mg/kg)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
