Nylidrin
CAY-33232-10 10 mg
Data Sheet: 
CAS
447-41-6
Formulation
A crystalline solid
Purity
≥85%
MW
299,40734
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors; binds to β-adrenergic receptors (Kd = 0.37 µM) and activates adenylate cyclase (Ka = 1.3 µM); selective for NR1A/2B over NR1A/2A and NR1A/2C subunit-containing NMDA receptors (IC50s = 0.18, 32, and 42 µM, respectively); inhibits NMDA-induced responses in primary rat cortical neurons (IC50 = 0.22 µM); decreases blood pressure and increases heart rate in SHRs (MED = 0.5 mg/kg); inhibits influenza hemagglutinin 2-mediated membrane fusion in Vero E6 cells at 20 and 100 µM; inhibits infection of MDCK cells by H1N1 and H3N2 influenza isolates in vitro (EC50s = 7.2 and 12.1 µM, respectively) and prevents infection in a mouse model of mouse-adapted H1N1 infection
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
