Synonyms: LSN3154567|Nicotinamide Phosphoribosyltransferase-IN-1


CAS
1698878-14-6
Formulation
A solid
Purity
≥98%
MW
419,49572
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A potent Nampt inhibitor (IC50 = 3.1 nM); selective for Nampt over a panel of >100 human kinases at 1 μM; inhibits NAD+ formation in and proliferation of HCT116 cells (IC50s = 1.8 and 8.9 nM, respectively); inhibits cell growth in a panel of cancer cell lines (IC50s = + formation in an A2780 ovarian carcinoma mouse xenograft model (ED50 = 2 mg/kg)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).