NS 3623
CAY-34992-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
343630-41-1
Formulation
A solid
Purity
≥95%
MW
427,178949
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An ion channel modulator; inhibits the VRAC in HEK293 cells and chloride conductance in isolated human red blood cells (IC50s = 1.8 and 0.21 µM, respectively); activates hERG/Kv11.1 (EC50 = 79.4 µM) but does not activate Kv1.5, Kv4.3, or Kv7.1 at 30 µM; increases red blood cell density and improves red blood cell morphology in the SAD transgenic mouse model of sickle cell disease at 100 mg/kg per day for 21 days; reverses E-4031-induced QT interval prolongation in conscious guinea pigs at 50 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
