NNC 05-2090 (hydrochloride)
CAY-42491-50 50 mg
Data Sheet: 
SDS:
SDS:
CAS
184845-18-9
Formulation
A solid
Purity
≥98%
MW
451,00002
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A BGT1 antagonist (IC50 = 5.1 µM for the human transporter); inhibits mouse GAT1, mouse GAT2, mouse GAT3, rat SERT, rat NET, and rat DAT (IC50s = 29.62, 45.29, 22.51, 5.29, 7.91, and 4.08 µM, respectively, in CHO cells expressing the mouse or rat transporters); increases the latency to paw withdrawal in a mouse model of partial sciatic nerve ligation-induced allodynia when administered intravenously at 0.01 or 0.03 mg/kg; decreases immobility time in the forced swim test in mice at 2 mg/kg; inhibits sound-induced clonic and tonic seizures and maximal electroshock-induced seizures in mice (ED50s = 26, 19, and 73 µmol/kg, respectively).
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
